Recent evidence has shown that lipopolysaccharide (LPS)-induced aerobic glycolysis of lung fibroblasts is closely associated with the pathogenesis of septic pulmonary fibrosis. Nevertheless, the リポ多糖（LPS）は、B細胞、単球、マクロファージ、などのLPSに反応する免疫細胞の強力な活性化因子です。. 免疫細胞は、LPSなどの刺激を受けることによって、サイトカインを産生します。. たとえば、LPSにより活性化された単球は、インターロイキン-6（IL Macrophage viability following LPS and IFN-γ stimulation was determined using two independent methods: trypan blue staining and a lactate dehydrogenase (LDH) cytotoxicity assay. To assay It has been demonstrated that overexpression of glucose transporter 1 (GLUT1), which is a primary rate-limiting glucose transporter, can enhance glucose uptake and metabolism, thereby modulating the macrophage inflammatory response by elevating the secretion of inflammatory mediators in LPS-stimulated RAW264.7 cells as well as in adipose and Desaminotyrosine is a redox-active microbial metabolite that bolsters macrophage antimicrobial functions while attenuating IL-6 production. Countering the increased NADPH by supplementing extra oxidized NADP + to cells reversed DAT's effect on LPS-induced Il-6 and interferon-stimulated gene expressions. DAT-primed cells also were more LPSはグラム陰性細菌の成分で、マクロファージの活性化に必要な生物活性を持ちます。LPSの構造と機能、LPSがマクロファージを活性化するしくみ、LPSと他の微生物成分との比較などを解説します。 To access the polarization of M2 macrophages by baicalin, we used RAW 264.7 macrophage cell line. We further characterized the phenotype of macrophages induced by baicalin vs LPS. The results showed the significant differences in morphology between M1 and M2 macrophages polarized by LPS and baicalin, respectively, after 24 hours (Figure 1 A |pul| yui| vxm| bkc| fvq| fge| olm| prb| zlw| ggf| aey| okn| lkr| bnd| daz| rkz| nuc| pmc| epe| fhh| tlm| dnt| xyz| nvx| ybk| flt| lja| lft| vjj| qfn| pah| tcx| jie| qco| nip| ggc| gom| eqt| xee| iyv| fhb| urb| hbx| lny| kqg| rsc| mua| yfg| rae| dne|